Share on PinterestAmy Schumer (above) asserts that she had to discontinue taking Ozempic shortly after she initiated because she encountered harsh side effects. MEGA/GC Images
During an interview on Watch What Happens Live with Andy Cohen, comedian Amy Schumer discussed that she tried taking the type 2 diabetes drug Ozempic for weight loss last year but discontinued after she experienced severe side effects that left her feeling weak and fatigued.
Ozempic, alongside drugs like Wegovy and Mounjaro, belongs to a class of medications referred to as glucagon-like peptide 1 (GLP-1) agonists.
They operate by triggering the body to generate more insulin, which aids in reducing blood sugar levels. Additionally, they curtail appetite and hinder gastric emptying, causing individuals to consume less food.
These medications are typically secure and most individuals tolerate them well, but they might entail hazards and engender unpleasant side effects in the gastrointestinal tract.
Schumer, 43, ultimately concluded that Ozempic’s side effects were interfering with her quality of life and that the drug was not “livable” for her.
“I was one of those people that felt so sick and couldn’t play with my son. I was so skinny and he’s throwing a ball at me and [I couldn’t],” Schumer revealed.
Regarding GLP-1 medications, it takes around four weeks of weekly injections to attain a steady state.
“Although certain patients are capable of tolerating more rapid dose escalation, gradually increasing the dose can contribute to tolerability,” Tan stated.
Since side effects such as vomiting and diarrhea can lead to dehydration and impact kidney function, it is crucial to consume an ample amount of fluids while taking these medications, according to Horn.
Horn also recommends paying heed to cues of fullness. By diminishing portion sizes, abstaining from high-fat foods, eating every few hours, and ceasing consumption when feeling full, one can decrease the chances of developing nausea, says Horn.
Houghton asserts that anyone using GLP-1 drugs, like Wegovy or Ozempic, for weight loss should bear in mind that they might experience nausea, vomiting, stomach pain, constipation, or diarrhea.
These side effects generally improve as individuals accustom themselves to the medications, states Cutler.
If nausea and vomiting impede your ability to retain any substances or hinder your functionality, consult with your healthcare provider.
If you develop severe abdominal pain (indicative of pancreatitis) or extreme debilitation, proceed to the emergency room, as recommended by Houghton.
Other side effects are less prevalent, but they can still transpire, claims Tan.
“However, if any new and atypical symptoms manifest after commencing these medications, patients should contact their healthcare providers,” she advised.
Amy Schumer shared that she attempted taking Ozempic for weight loss last year but discontinued after she developed serious side effects that left her feeling weak and fatigued.
Pharmaceuticals like Ozempic diminish appetite and decelerate gastric emptying, inducing individuals to consume less food.
They are generally secure but they might entail hazards and engender unpleasant side effects in the gastrointestinal tract.
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